Most grand slam home runs in a game According to Official Guinness Records,
The Major League Baseball (MLB) record for most grand slam home runs hit in a game is 2 by 13 players, most recently Josh Willingham (USA) playing for the Washington Nationals (USA) against the Milwaukee Brewers (USA) on 27 July 2009. For a complete list of 2009 records, please visit 2009 Guinness Records in United States .
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