This is a compilation of 40 United States Guinness records in 2001. You may want to take a look at our complete list of United States Guinness Records broken down by year.
| When | Record name | What | Who |
|---|---|---|---|
| 26 October 2001 | Farthest auto accident flight survived | Matt McKnight | |
| 26 October 2001 | Most countries visited in a continuous journey by car | 111 total number | Jim Rogers , Paige Parker |
| 21 October 2001 | Largest pair of bib overalls | Shawnee Garment Manufacturing Company | |
| 18 October 2001 | Fastest wheel-driven vehicle | 737.794 kilometre(s) per hour | Don Vesco |
| 18 October 2001 | Fastest turbine-powered car | 737.794 kilometre(s) per hour | Don Vesco |
| 16 October 2001 | Fastest lugeing speed | 139.39 kilometre(s) per hour | Tony Benshoof |
| 08 October 2001 | Most expensive literature by Shakespeare sold at auction | 6166000 US dollar(s) | The First Folio |
| 30 September 2001 | Largest severance package | 417,000,000 US dollar(s) | Jack Welch |
| 28 September 2001 | Highest ranked US officer charged with espionage | George Trofimoff | |
| 18 September 2001 | Most heads on one sunflower | Melvin Hemker | |
| August 2001 | Longest duration lip trill | Robert Uomini | |
| 16 July 2001 | Hang gliding - most consecutive loops | 95 total number | Chad Elchin |
| 02 July 2001 | First self-contained mechanical heart implant | first | Jewish Hospital |
| 07 June 2001 | Largest fuel tank fire | 37000000 litre(s) | Unknown |
| 27 May 2001 | Largest sleeping bag | Slumberjack | |
| May 2001 | Oldest practising doctor (ever) | Dr. Leila Denmark | |
| 23 April 2001 | Sack race - fastest 10km | 1/22/2 hour(s):minute(s):second(s) | Ashrita Furman |
| 03 April 2001 | Oldest operating bourbon distillery | Unknown | |
| 12 March 2001 | Most consecutive zip codes identified | 36 total number | David Rosdeitcher |
| 20 February 2001 | Highest 8-person tightrope pyramid | The Flying Wallendas | |
| 14 February 2001 | Longest lawn mower ride | Gary Hatter | |
| 31 January 2001 | Fastest bicycle wheelie - rear wheel | 138.56 kilometre(s) per hour | Bobby Root |
| 31 January 2001 | Fastest bicycle wheelie - front wheel | 94.62 kilometre(s) per hour | Bobby Root |
| 28 January 2001 | Youngest person to play in the Super Bowl | Jamal Lewis | |
| 27 January 2001 | Largest single donation to AIDS research | 100000000 US dollar(s) | William H. Gates Foundation |
| 25 January 2001 | Longest golf hole-in-one in a PGA Tour event | 332 yard(s) | Andrew Magee |
| 21 January 2001 | Most backflips on a kick scooter- single jump | Jarret Reid | |
| 21 January 2001 | Highest jump on a motorcycle | Tommy Clowers | |
| 20 January 2001 | Most backflips (single leap) - in-line skates | 2 total number | Jason Stinsmen |
| 14 January 2001 | Largest amount of corn harvested by a single combine harvester in eight hours | 19196.59 tonne(s)/metric ton(s) | James C. (Jay) Justice III |
| 12 January 2001 | Fastest atomic clock | National Institute of Standards and Technology | |
| 03 January 2001 | First first lady to win elected office | first | Hillary Clinton |
| 01 January 2001 | Largest producer of antimatter | Fermilab | |
| January 2001 | Densest matter | 20:1 ratio | Unknown |
| January 2001 | Slowest light | first | US scientists |
| 2001 | Largest unmanned submarine | LSV-2 Cutthroat | |
| 2001 | Oldest competitive pool player | Wesley Walker | |
| 2001 | Most bridges walked across | Donald H. Betty | |
| 2001 | Largest covered wagon | 12.2/3.65/7.6 metre(s) | David R. Bentley |
| 2001 | Most valuable bra | 12,500,000 US dollar(s) | Heavenly Star Bra, by Victoria's Secret |