| First player with 20 interceptions and 20 QB sacks in an NFL career | first | Rodney Harrison |
| Most expensive jeans | 10000 US dollar(s) | Escada |
| Highest point scoring average in NBA playoff games | | Michael Jordan |
| First animal whose evidence is admissible in court | first | Bloodhound |
| Greatest Budget fiscal surplus | 11796000000 US dollar(s) | United States |
| Largest collection of valid credit cards | | Walter Cavanagh |
| Best-selling solo artist | 1000000000 unit(s) sold | Elvis Presley |
| Fastest military aircraft, operational bomber | | General Dynamics FB-111A |
| Most people crammed in a Purikura booth simultaneously | 27 people | Japantown, San Francisco, USA |
| Most rainy days | | Wai‘ale‘ale |
| Oldest X Games medallist | | Angelika Casteneda |
| First person to win $100,000 on a television game show | 150000 US dollar(s) | Barbara Phillips |
| First computer virus | first | Unknown |
| Cherry stone spitting - greatest distance | 28.51 metre(s) | Brian Krause |
| First rookie to win NBA sixth man award | first | Ben Gordon |
| Heaviest model | | Unknown |
| Most documented tournament wins for a gaming team | 2,000 total number | Empire Arcadia |
| First execution by lethal injection | 1983/12/07 first | Unknown |
| First concert simultaneously held in a real and virtual space | first | The Dares, Free Realms (SOE, 2009) |
| First player to win NBA titles with three franchises | first | John Salley |
| First mammal | first first | Unknown |
| First father v son NBA match | first | Jan Van Breda Kolff, Butch Van Breda Kolff |
| Largest Easter egg hunt | | Adventure Parks Group, LLC |
| First execution by electric chair | first | Unknown |
| Most children fathered by a US president | 15 people | John Tyler |
| First concert held in a real and a virtual space simultaneously | first | The Dares (USA) |
| First videogame to use serving soldiers as characters | first | America's Army (US Army, 2002;Ubisoft, 2005) |
| Heaviest tank (present day) | 63 tonne(s)/metric ton(s) | M1A2 Abrams tank |
| First foreign language film to earn over $100 million in the USA | first | Wo Hu Cang Long (aka Crouching Tiger, Hidden Dragon) (Tpe 2000) |
| Largest Vacuum Cleaner | | Discovery Channel BIG! |
| Most consecutive footbag kicks - doubles | | Tricia George, Gary Lautt |
| First graphic novel | first | Richard Corben |
| Highest score on 720°Degrees (Arcade) | | Ron Perelman (USA) |
| First bird | first first | Protoavis texensis |
| First 3D movie to win Best Cinematography Oscar | first | Avatar |
| Smallest autopilot | | Procerus Technologies |
| Rarest boxwood | | Vahl's boxwood |
| Largest knitted/crocheted stocking | 712.54 square metre(s) | Caron |
| Highest margin of victory on Madden NFL 09 (EA, 2008) | | Patrick Scott Patterson |
| Largest crew on a warship | 5,680 people | Nimitz class |
| Longest monster truck | 9.75 metre(s) | Jen and Brad Campbell |
| Longest birthday card exchange | | Pat Shardelow |
| First person with 30 stolen bases, 30 home runs, 30 doubles, 20 triples in one Major League Baseball | first | Jimmy Rollins |
| Telephone - smallest | | Jan Piotr Krutewicz |
| Best selling single of instrumental music | 2000000 unit(s) sold | John Williams (composer) |
| Most Indianapolis 500 Wins | 4 total number | A. J. Foyt Jr., Al Unser Sr., Rick Mears |
| Fastest completion of Katamari Damacy | 30/26 minute(s):second(s) | Tom Batchelor |
| Fastest speed skating [long track] 5,000 m (female) | | Tommy Clowers, Brian Deegan, Mike Metzger, Mike Jones, Caleb Wyatt |
| Oldest driver - ever (male) | 104 year(s):day(s) | Fred Hale |
| Largest submillimetre telescope | | James Clerk Maxwell Telescope |
| First hominid to survive a space flight | first | Unknown |
| Best-selling action sports videogame | 2000000 unit(s) sold | Tony Hawk’s Pro Skater 2 (Activision, 2000) |
| First stealth ship | | US Navy Sea Shadow |
| Largest library book fine paid | 345.14 US dollar(s) | Emily Canellos-Simms |
| Highest score on Marvel Vs. Capcom 2 | | Zach Robinson (USA) |
| Fastest completion of LostWinds | | Justin Salamon |
| Longest toe | 12.7 centimetre(s) | Matthew McGrory |
| First Xbox 360 videogame to use kiosk downloads | first | Burnout Revenge |
| Most married Hollywood stars | | Stan Laurel, Georgia Holt, Lana Turner, Mickey Rooney, Zsa Zsa Gabor, Elizabeth Taylor |
| Most Nobel Science Prize winners from one laboratory | 11 people | Bell Laboratories |
| Longest length contributed by a player on Noby Noby Boy | | SSSS7960 (USA) |
| Tallest player in NHL ice hockey | | Zdeno Chara |
| Largest tilting ship | | FLIP |
| First to accumulate one million followers on Twitter | first first | Ashton Kutcher |
| First cartoon merchandise | first | Unknown |
| Most resistant insect | | Myzus persicae |
| Largest aluminium foil ball (aluminum) | 1615 kilogram(s) | Richard Roman |
| Smallest knife | first | Knife made by the National Institute of Standards and Technology |
| Oldest living people to share a birthday | | Henry Allingham, George Francis |
| Deepest bat colony | | Unknown |
| Farthest cow pat toss | | Steve Urner |
| Largest object transported by air | | Space Shuttle |
| Largest hospital ship | | USNS Mercy Class |
| High diving - highest scored dive | 159.00 point(s) | Orlando Duque |
| First circumnavigation by walking | first | George Mathew Schilling, David Kunst |
| Highest score on Tony Hawk’s Pro Skater 2: Hangar Level | | Matt Tholen (USA) |
| First rocket launch | 1926/03/16 first | Unknown |
| Longest reigning boxing world champion | | Joe Louis |
| Most successful chimpanzee on Wall Street | 213 percentage | Raven the chimpanzee |
| Smallest guided missile | | USA |
| First radio transmission | | Unknown |
| Largest warship | 317 metre(s) | Nimitz class |
| Smallest dog living (length) | 15.2 centimetre(s) | Brandy |
| Fastest completion of Virtua Tennis | | Jan-Erik P Spangberg |
| Most expensive species in captivity | 1000000 US dollar(s) | Giant panda (Ailuropoda melanoleuca) |
| Youngest radio presenter | 5 year(s):day(s) | Kimberley Perez |
| First rap awards | first | Jazzy Jeff and the Fresh Prince |
| Most consecutive days surfing | | Dale Webster |
| Largest navy by aircraft | | US Navy |
| Largest hands ever | 32.3 centimetre(s) | Robert Wadlow |
| First GPS projectile tracking device | first | StarChase |
| Most bioluminescent insect | 45 total number | Pyrophorus noctilucus |
| Smallest centipede | 10.3 millimetre(s) | Nannarrup hoffmani |
| Most complex laser system | | National Ignition Facility (NIF) |
| Most Billboard Hot 100 entries by a solo artist (female) | | Nicki Minaj |
| First identified impact crater | | Yosemite |
| First person in Major League Baseball with 2,000 wins as manager and 2,000 hits as player | first | Joe Torre |
| Tallest mountain | 10205 metre(s) | Mauna Kea |
| Shortest player in NHL ice hockey | | Brian Gionta |
| Undefeated heavyweight world champion, Boxing | 49 total number | Unknown |
| Longest pipelines - oil | | Unknown |
| Highest points total on Columns (Mega Drive version) | | Keith Danforth (USA) |
| Most fakie kickflips on a skateboard in one minute | 24 total number | Chris Cole |
| Longest earlobes - stretched | 12.7/11.43 centimetre(s) | Monte Pierce |
| First broadcast | first | Unknown |
| Oldest X Games athlete | | Angelika Casteneda |
| Largest collection of books owned privately | | John Q. Benham |
| Largest mudflow from a volcano | 3000000000 cubic metre(s) | Osceola Mudflow |
| Most endangered fish | | Unknown |
| Only actors to win Best Director Oscar | | Mel Gibson, Clint Eastwood, Woody Allen, Robert Redford, Kevin Costner |
| Largest wooden baseball bat | | Fargo-Moorhead RedHawks |
| Heaviest chicken egg | 454 gram(s) | Unknown |
| Most home runs in a Major League Baseball career | 762 total number | Barry Bonds |
| Most feet and armpits sniffed | 5600 total number | Madeline Albrecht |
| Fastest lap on Ridge Racer (high level) | 1/0.757 minute(s):second(s) | Alex T Trammell (USA) |
| Widest canal | | Cape Cod Canal |
| Smallest microchain drive | | Sandia National Laboratories |
| Highest score on Beyond Good &Evil | | Kenneth Ray Craig Jr (USA) |
| First player to play 400 NHL ice hockey matches with three different teams | first | Chris Chelios |
| Biggest blowout on NHL 94 | | Kyle Waters |
| Highest paid child actress on TV by episode | 180000 US dollar(s) | Miranda Cosgrove |
| First soap opera | first | Painted Dreams |
| Most prolific cat | | Unknown |
| Youngest figure skating world champion | | Unknown |
| Largest hangar - free standing | | Hangar 375 |
| Smallest cat ever | 7/19 centimetre(s) | Tinker Toy, owned by Scott Forbes |
| Largest drillship | | Discoverer class vessels |
| Fastest 10 m on a walking globe by a dog | 33.22 second(s) | Sailor |
| First film remastered in 3D | first | Toy Story 3D (USA, 2010) |
| Most generations to celebrate a golden wedding anniversary (50th) | 5 total number | James Heim |